Description

7-deaza-2′-deoxyguanosine-5′-triphosphate
7-deaza-dGTP may be effectively incorporated into the DNA by DNA polymerases and/or terminal deoxynucleotidyl transferase. 7-deaza-dG - containing DNA duplexes demonstrate increased stability, 7-deaza-dG - containing DNA penetrates cell membrane more effectively due to the increased lypophility.
7-deaza dGTP may be used in sequencing for the resolution of the compressions in G-C-rich regions. Amplification of some DNA regions is often hindered due to the high G-C content. Replacement of dGTP to 7-deaza dGTP in the master mix may solve the problems.

Storage Condition

-20°C .

Concentration

1 µmol (100 µl of 10 mM solution)

Purity

96-99% (HPLC).

Formula

C₁₁H₁₇N₄O₁₃P₃,  Molecular Weight (506.2)