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Membrane Receptor Research

Membrane receptors play key roles in cellular processes including transport of molecules, signal transduction, utilization of energy, and maintenance of cell and tissue structures. It has been determined by genome sequencing that around 30% of genes encode membrane receptors. Furthermore, they are pharmacologically significant as half of the current drugs target the membrane receptors.

Here eEnzyme is proud to introduce first cataloged products for membrane receptor research, including a broad range of functional receptors in form of stable cell lines and membrane preparations, suitable for purification and related applications (ligand binding assays, SPR, antibody selection, NMR and Xray crystallography).


Tetracycline inducible cell lines (CHO/HEK293)
Receptor enriched membrane preparations produced from highly expressing cell lines
Affinity purified by streptactin and/or nickel/cobalt column

ION CHANNELS

Gaba

Glycine

Potassium channel

Purinoceptor

Serotonin

Zinc activated ion channel

 

 

 

GPCRs

Adenosine

Adrenergic

Angiotensin

Bombesin

Bradykinin

Calcitonin

Calcium sensing

Cannabinoid

Chemokine

Cholecystokinin

Complement peptide

Corticotropin-releasing factor

Dopamine

Endothelin

Estrogen

Formylpeptide

Free fatty acid R

Frizzled

Galanin

Gastrin/Cholecystokinin

Ghrelin receptor

Glucagon family receptors

Glycoprotein hormone receptors

Gonadotropin-releasing hormone

Histamine

Hydroxycarboxylic acid

Leukotriene

Lysophosphatidic acid

Melanin-concentrating hormone

Melanocortin

Melatonin

Metabotropic glutamate

Metastin

Muscarinic acetylcholine

Neuromedin U

Neuropeptide Y

Olfactory

Opioid

Opsin

Orexin

Orphan receptors

Prokineticin

Prolactin-releasing peptide

Prostanoid

Proteinase activated

Purinergic

Relaxin

Rhodopsin

Secretin

Serotonin

Somatostatin

Sphingosine 1-phosphate

Tachykinin

Thyroid/Parathyroid hormone

Trace Amine

Vasopressin and oxytocin

VIP & PACAP

Other GPCRs