|
|
|
Human Cancer Drug Resistance Metabolism qPCR Array
|
|
|
2 or 12 plates Included plus qPCR MasterMix
|
Price: From $199.00 to $1,199.00
Product Options
| |
| |
Detailed Description
This Cancer Drug Resistance Metabolism Array is
designed to profile the expression of 88 key genes involved involved in the
body's response to chemotherapy and
4 house-keeping
genes.
Features
- More genes featured for each pathway
- Fits to ABI, BioRad and many other Real-Time thermocyclers
- Strong detection signals without leaking to
the adjacent wells
- Higher sensitivity and sharper melting curve
- All sets of primers span at least one intron of
the genomic sequence with annealing temperatures of 60 ± 1 oC
- EvaGreen PCR MasterMix (2x) included
|
Catalog Number
|
qPCR Array Format
|
Real-Time Thermal Cyclers
|
|
GA-C117A
|
Human Cancer Drug
Resistance Metabolism qPCR
Array Format A
|
Bio-Rad CFX96, CFX384;
Bio-Rad/MJ Research models Chrom4, DNA Engine Bio-Rad models iCycler, iQ5,
MyiQ, MyiQ2, Opticon 2; Roche LightCycler 480 (96).
|
|
GA-C117B
|
Human Cancer Drug
Resistance Metabolism qPCR
Array Format B
|
Applied Biosystems models 5700, 7300, 7500
(Standard and Fast), 7700, 7900HT (Standard and Fast); StepOnePlus, ViiA7
(Standard and Fast);
Eppendorf Mastercycler ep realplex models 2, 2S, 4, 4S; Stratagene models Mx3000P, Mx3005P, Mx4000;
Takara TP-800.
|
Gene Information
|
Position
|
GeneBank
|
Symbol
|
Gene Name
|
|
A01
|
NM_000927
|
ABCB1
|
ATP-binding cassette, sub-family B (MDR/TAP), member 1
|
|
A02
|
NM_004996
|
ABCC1
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
|
|
A03
|
NM_000392
|
ABCC2
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
|
|
A04
|
NM_003786
|
ABCC3
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
|
|
A05
|
NM_005688
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
|
A06
|
NM_001171
|
ABCC6
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
|
|
A07
|
NM_004827
|
ABCG2
|
ATP-binding cassette, sub-family G (WHITE), member 2
|
|
A08
|
NM_001621
|
AHR
|
Aryl hydrocarbon receptor
|
|
A09
|
NM_001283
|
AP1S1
|
Adaptor-related protein complex 1, sigma 1 subunit
|
|
A10
|
NM_000038
|
APC
|
Adenomatous polyposis coli
|
|
A11
|
NM_000044
|
AR
|
Androgen receptor
|
|
A12
|
NM_001668
|
ARNT
|
Aryl hydrocarbon receptor nuclear translocator
|
|
B01
|
NM_000051
|
ATM
|
Ataxia telangiectasia mutated
|
|
B02
|
NM_004324
|
BAX
|
BCL2-associated X protein
|
|
B03
|
NM_000633
|
BCL2
|
B-cell CLL/lymphoma 2
|
|
B04
|
NM_138578
|
BCL2L1
|
BCL2-like 1
|
|
B05
|
NM_000386
|
BLMH
|
Bleomycin hydrolase
|
|
B06
|
NM_007294
|
BRCA1
|
Breast cancer 1, early onset
|
|
B07
|
NM_000059
|
BRCA2
|
Breast cancer 2, early onset
|
|
B08
|
NM_053056
|
CCND1
|
Cyclin D1
|
|
B09
|
NM_001238
|
CCNE1
|
Cyclin E1
|
|
B10
|
NM_001798
|
CDK2
|
Cyclin-dependent kinase 2
|
|
B11
|
NM_000075
|
CDK4
|
Cyclin-dependent kinase 4
|
|
B12
|
NM_000389
|
CDKN1A
|
Cyclin-dependent kinase inhibitor 1A (p21, Cip1)
|
|
C01
|
NM_004064
|
CDKN1B
|
Cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
|
C02
|
NM_000077
|
CDKN2A
|
Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
|
|
C03
|
NM_001800
|
CDKN2D
|
Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
|
|
C04
|
NM_030782
|
CLPTM1L
|
CLPTM1-like
|
|
C05
|
NM_000499
|
CYP1A1
|
Cytochrome P450, family 1, subfamily A, polypeptide 1
|
|
C06
|
NM_000761
|
CYP1A2
|
Cytochrome P450, family 1, subfamily A, polypeptide 2
|
|
C07
|
NM_000767
|
CYP2B6
|
Cytochrome P450, family 2, subfamily B, polypeptide 6
|
|
C08
|
NM_000769
|
CYP2C19
|
Cytochrome P450, family 2, subfamily C, polypeptide 19
|
|
C09
|
NM_000770
|
CYP2C8
|
Cytochrome P450, family 2, subfamily C, polypeptide 8
|
|
C10
|
NM_000771
|
CYP2C9
|
Cytochrome P450, family 2, subfamily C, polypeptide 9
|
|
C11
|
NM_000106
|
CYP2D6
|
Cytochrome P450, family 2, subfamily D, polypeptide 6
|
|
C12
|
NM_000773
|
CYP2E1
|
Cytochrome P450, family 2, subfamily E, polypeptide 1
|
|
D01
|
NM_017460
|
CYP3A4
|
Cytochrome P450, family 3, subfamily A, polypeptide 4
|
|
D02
|
NM_000777
|
CYP3A5
|
Cytochrome P450, family 3, subfamily A, polypeptide 5
|
|
D03
|
NM_000791
|
DHFR
|
Dihydrofolate reductase
|
|
D04
|
NM_005228
|
EGFR
|
Epidermal growth factor receptor
|
|
D05
|
NM_005229
|
ELK1
|
ELK1, member of ETS oncogene family
|
|
D06
|
NM_000120
|
EPHX1
|
Epoxide hydrolase 1, microsomal (xenobiotic)
|
|
D07
|
NM_004448
|
ERBB2
|
V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma
derived oncogene homolog (avian)
|
|
D08
|
NM_001982
|
ERBB3
|
V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
|
|
D09
|
NM_005235
|
ERBB4
|
V-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
|
|
D10
|
NM_000122
|
ERCC3
|
Excision repair cross-complementing rodent repair deficiency,
complementation group 3 (xeroderma pigmentosum group B complementing)
|
|
D11
|
NM_000125
|
ESR1
|
Estrogen receptor 1
|
|
D12
|
NM_001437
|
ESR2
|
Estrogen receptor 2 (ER beta)
|
|
E01
|
NM_002006
|
FGF2
|
Fibroblast growth factor 2 (basic)
|
|
E02
|
NM_005252
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
|
E03
|
NM_019884
|
GSK3A
|
Glycogen synthase kinase 3 alpha
|
|
E04
|
NM_000852
|
GSTP1
|
Glutathione S-transferase pi 1
|
|
E05
|
NM_001530
|
HIF1A
|
Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix
transcription factor)
|
|
E06
|
NM_000875
|
IGF1R
|
Insulin-like growth factor 1 receptor
|
|
E07
|
NM_000876
|
IGF2R
|
Insulin-like growth factor 2 receptor
|
|
E08
|
NM_000245
|
MET
|
Met proto-oncogene (hepatocyte growth factor receptor)
|
|
E09
|
NM_000251
|
MSH2
|
MutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
|
|
E10
|
NM_017458
|
MVP
|
Major vault protein
|
|
E11
|
NM_002467
|
MYC
|
V-myc myelocytomatosis viral oncogene homolog (avian)
|
|
E12
|
NM_000015
|
NAT2
|
N-acetyltransferase 2 (arylamine N-acetyltransferase)
|
|
F01
|
NM_003998
|
NFKB1
|
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
|
|
F02
|
NM_002502
|
NFKB2
|
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
(p49/p100)
|
|
F03
|
NM_002503
|
NFKBIB
|
Nuclear factor of kappa light polypeptide gene enhancer in B-cells
inhibitor, beta
|
|
F04
|
NM_004556
|
NFKBIE
|
Nuclear factor of kappa light polypeptide gene enhancer in B-cells
inhibitor, epsilon
|
|
F05
|
NM_005036
|
PPARA
|
Peroxisome proliferator-activated receptor alpha
|
|
F06
|
NM_006238
|
PPARD
|
Peroxisome proliferator-activated receptor delta
|
|
F07
|
NM_015869
|
PPARG
|
Peroxisome proliferator-activated receptor gamma
|
|
F08
|
NM_000964
|
RARA
|
Retinoic acid receptor, alpha
|
|
F09
|
NM_000965
|
RARB
|
Retinoic acid receptor, beta
|
|
F10
|
NM_000966
|
RARG
|
Retinoic acid receptor, gamma
|
|
F11
|
NM_000321
|
RB1
|
Retinoblastoma 1
|
|
F12
|
NM_006509
|
RELB
|
V-rel reticuloendotheliosis viral oncogene homolog B
|
|
G01
|
NM_002957
|
RXRA
|
Retinoid X receptor, alpha
|
|
G02
|
NM_021976
|
RXRB
|
Retinoid X receptor, beta
|
|
G03
|
NM_000454
|
SOD1
|
Superoxide dismutase 1, soluble
|
|
G04
|
NM_005420
|
SULT1E1
|
Sulfotransferase family 1E, estrogen-preferring, member 1
|
|
G05
|
NM_003839
|
TNFRSF11A
|
Tumor necrosis factor receptor superfamily, member 11a, NFKB activator
|
|
G06
|
NM_003286
|
TOP1
|
Topoisomerase (DNA) I
|
|
G07
|
NM_001067
|
TOP2A
|
Topoisomerase (DNA) II alpha 170kDa
|
|
G08
|
NM_001068
|
TOP2B
|
Topoisomerase (DNA) II beta 180kDa
|
|
G09
|
NM_000546
|
TP53
|
Tumor protein p53
|
|
G10
|
NM_005359
|
SMAD4
|
SMAD family member 4
|
|
G11
|
NM_000594
|
TNF
|
Tumor necrosis factor
|
|
G12
|
NM_005080
|
XBP1
|
X-box binding protein 1
|
|
H01
|
NM_004048
|
B2M
|
Beta-2-microglobulin
|
|
H02
|
NM_004456.4
|
EZH2
|
Enhancer of zeste homolog 2 (Drosophila) (EZH2)
|
|
H03
|
NM_012423
|
RPL13A
|
Ribosomal protein L13a
|
|
H04
|
NM_003403.3
|
YY1
|
Homo sapiens YY1 transcription factor (YY1),
|
|
H05
|
BSG-PA1
|
HGD1
|
Human Genomic DNA -1
|
|
H06
|
BSG-PA2
|
HGD2
|
Human Genomic DNA -2
|
|
H07
|
NM_002046
|
GAPDH
|
Glyceraldehyde-3-phosphate dehydrogenase
|
|
H08
|
NM_002046
|
GAPDH
|
Glyceraldehyde-3-phosphate dehydrogenase
|
|
H09
|
NM_001101
|
ACTB
|
Actin, beta
|
|
H10
|
NM_001101
|
ACTB
|
Actin, beta
|
|
H11
|
NM_006082.2
|
TUBA1B
|
Tubulin, alpha 1b
|
|
H12
|
NM_000194
|
HPRT1
|
Hypoxanthine phosphoribosyltransferase 1
|
qPCR Array Layout
(96-Well)
|
|