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Human Cancer Drug Target qPCR Array
2 or 12 plates Included plus qPCR MasterMix
Price: From $199.00 to $1,199.00

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Detailed Description

This Cancer Drug Target Array is designed to profile the expression of 88 key genes or targets for anticancer therapeutics and drug development.

Features

  • More genes featured for each pathway
  • Fits to ABI, BioRad and many other Real-Time thermocyclers
  • Strong detection signals without leaking to the adjacent wells
  • Higher sensitivity and sharper melting curve
  • All sets of primers span at least one intron of the genomic sequence with annealing temperatures of 60 ± 1 oC
  • EvaGreen PCR MasterMix (2x) included

Catalog Number

qPCR Array Format

Real-Time Thermal Cyclers

GA-C118A

Human Cancer Drug Target qPCR Array Format A

Bio-Rad CFX96, CFX384; Bio-Rad/MJ Research models Chrom4, DNA Engine Bio-Rad models iCycler, iQ5, MyiQ, MyiQ2, Opticon 2; Roche LightCycler 480 (96).

GA-C118B

Human Cancer Drug Target qPCR Array Format B

Applied Biosystems models 5700, 7300, 7500 (Standard and Fast), 7700, 7900HT (Standard and Fast); StepOnePlus, ViiA7 (Standard and Fast); Eppendorf Mastercycler ep realplex models 2, 2S, 4, 4S; Stratagene models Mx3000P, Mx3005P, Mx4000; Takara TP-800.

Gene Information

Position GeneBank Symbol Gene Name
A01 NM_004996 ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
A02 NM_005163 AKT1 V-akt murine thymoma viral oncogene homolog 1
A03 NM_001626 AKT2 V-akt murine thymoma viral oncogene homolog 2
A04 NM_001880 ATF2 Activating transcription factor 2
A05 NM_003600 AURKA Aurora kinase A
A06 NM_004217 AURKB Aurora kinase B
A07 NM_003160 AURKC Aurora kinase C
A08 NM_000633 BCL2 B-cell CLL/lymphoma 2
A09 NM_001168 BIRC5 Baculoviral IAP repeat containing 5
A10 NM_001786 CDK1 Cyclin-dependent kinase 1
A11 NM_001789 CDC25A Cell division cycle 25 homolog A (S. pombe)
A12 NM_001798 CDK2 Cyclin-dependent kinase 2
B01 NM_000075 CDK4 Cyclin-dependent kinase 4
B02 NM_004935 CDK5 Cyclin-dependent kinase 5
B03 NM_001799 CDK7 Cyclin-dependent kinase 7
B04 NM_001260 CDK8 Cyclin-dependent kinase 8
B05 NM_001261 CDK9 Cyclin-dependent kinase 9
B06 NM_001908 CTSB Cathepsin B
B07 NM_001909 CTSD Cathepsin D
B08 NM_001912 CTSL1 Cathepsin L1
B09 NM_004079 CTSS Cathepsin S
B10 NM_005228 EGFR Epidermal growth factor receptor
B11 NM_004448 ERBB2 V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
B12 NM_001982 ERBB3 V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
C01 NM_005235 ERBB4 V-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
C02 NM_000125 ESR1 Estrogen receptor 1
C03 NM_001437 ESR2 Estrogen receptor 2 (ER beta)
C04 NM_004469 FIGF C-fos induced growth factor (vascular endothelial growth factor D)
C05 NM_002019 FLT1 Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
C06 NM_002020 FLT4 Fms-related tyrosine kinase 4
C07 NM_002086 GRB2 Growth factor receptor-bound protein 2
C08 NM_000852 GSTP1 Glutathione S-transferase pi 1
C09 NM_004964 HDAC1 Histone deacetylase 1
C10 NM_024827 HDAC11 Histone deacetylase 11
C11 NM_001527 HDAC2 Histone deacetylase 2
C12 NM_003883 HDAC3 Histone deacetylase 3
D01 NM_006037 HDAC4 Histone deacetylase 4
D02 NM_006044 HDAC6 Histone deacetylase 6
D03 NM_001098416 HDAC7 Histone deacetylase 7
D04 NM_018486 HDAC8 Histone deacetylase 8
D05 NM_001530 HIF1A Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
D06 NM_005343 HRAS V-Ha-ras Harvey rat sarcoma viral oncogene homolog
D07 NM_001017963 HSP90AA1 Heat shock protein 90kDa alpha (cytosolic), class A member 1
D08 NM_003299 HSP90B1 Heat shock protein 90kDa beta (Grp94), member 1
D09 NM_000618 IGF1 Insulin-like growth factor 1 (somatomedin C)
D10 NM_000875 IGF1R Insulin-like growth factor 1 receptor
D11 NM_000612 IGF2 Insulin-like growth factor 2 (somatomedin A)
D12 NM_001098629 IRF5 Interferon regulatory factor 5
E01 NM_002253 KDR Kinase insert domain receptor (a type III receptor tyrosine kinase)
E02 NM_000222 KIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
E03 NM_004985 KRAS V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
E04 NM_002392 MDM2 Mdm2 p53 binding protein homolog (mouse)
E05 NM_002393 MDM4 Mdm4 p53 binding protein homolog (mouse)
E06 NM_004958 MTOR Mechanistic target of rapamycin (serine/threonine kinase)
E07 NM_003998 NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
E08 NM_002524 NRAS Neuroblastoma RAS viral (v-ras) oncogene homolog
E09 NM_006181 NTN3 Netrin 3
E10 NM_001618 PARP1 Poly (ADP-ribose) polymerase 1
E11 NM_005484 PARP2 Poly (ADP-ribose) polymerase 2
E12 NM_006437 PARP4 Poly (ADP-ribose) polymerase family, member 4
F01 NM_006206 PDGFRA Platelet-derived growth factor receptor, alpha polypeptide
F02 NM_002609 PDGFRB Platelet-derived growth factor receptor, beta polypeptide
F03 NM_000926 PGR Progesterone receptor
F04 NM_002645 PIK3C2A Phosphoinositide-3-kinase, class 2, alpha polypeptide
F05 NM_002647 PIK3C3 Phosphoinositide-3-kinase, class 3
F06 NM_006218 PIK3CA Phosphoinositide-3-kinase, catalytic, alpha polypeptide
F07 NM_005030 PLK1 Polo-like kinase 1
F08 NM_006622 PLK2 Polo-like kinase 2
F09 NM_004073 PLK3 Polo-like kinase 3
F10 NM_014264 PLK4 Polo-like kinase 4
F11 NM_002737 PRKCA Protein kinase C, alpha
F12 NM_002738 PRKCB Protein kinase C, beta
G01 NM_006254 PRKCD Protein kinase C, delta
G02 NM_005400 PRKCE Protein kinase C, epsilon
G03 NM_000963 PTGS2 Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
G04 NM_001664 RHOA Ras homolog gene family, member A
G05 NM_004040 RHOB Ras homolog gene family, member B
G06 NM_198253 TERT Telomerase reverse transcriptase
G07 NM_003747 TNKS Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
G08 NM_001067 TOP2A Topoisomerase (DNA) II alpha 170kDa
G09 NM_001068 TOP2B Topoisomerase (DNA) II beta 180kDa
G10 NM_000546 TP53 Tumor protein p53
G11 NM_003329 TXN Thioredoxin
G12 NM_003330 TXNRD1 Thioredoxin reductase 1
H1 NM_005427 TP73  
H2 NM_001167 YY1 YY1 transcription factor
H3 NM_012423 RPL13A Ribosomal protein L13a
H4 NM_004048 B2M Beta-2-microglobulin
H5 BSG-PAH01 HGD1 Genomic DNA control 
H6 BSG-PAH02 HGD Genomic DNA control
H7 NM_002046 GAPDH Glyceraldehyde-3-phosphate dehydrogenase
H8 NM_002046 GAPDH Glyceraldehyde-3-phosphate dehydrogenase
H9 NM_001101 ACTB Actin, beta
H10 NM_001101 ACTB Actin, beta
H11 NM_006082.2 tuba1b Homo sapiens tubulin, alpha 1b (TUBA1B)
H12 NM_000194 HPRT1 Hypoxanthine phosphoribosyltransferase 1

qPCR Array Layout (96-Well)