8-oxo-2′-deoxyguanosine-5′-triphosphate

8-oxo-dGTP is a product of oxidative modification of dGTP that can be misincorporated into DNA, causing AT-->CG mutations. So the oxidized guanine (8-oxo-7,8-dihydroguanine; 8-oxo-G) is a potent mutagen due to its ambiguous pairing with cytosine and adenine.

Storage Condition

-20°C

Concentration

1 µmol (100 µl of 10 mM solution)

Purity

96-99% (HPLC)

Formula

C₁₀H₁₂N₅O₁₄P₃, MW 519.15 (Anion)

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