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ACTOne GPCR Stable Cell Lines

1) ACTOne GPCR assay is a live cell-based cAMP biosensor detection system generated for high-throughput functional screening of G-protein coupled receptors.

• Over 60 GPCR stable cell lines established and being developed

• Highly sensitive and big assay windows

• Excellent signal-to-noise ratio and reproducibility

• Real time kinetic assay or end point assay

• Work for both endogenous or recombinant GPCRs

• Agonist and antagonist screening in one assay


        Click below for a 22-page-ppt overview of the technology:

        


2) AbPlus GPCR HTS Assay System is a newly developed live cell-based assay platform for functional screening of Gi-coupled GPCR antibodies. This proprietary TRPC biosensor has been modulated specifically to detect Gi-coupled GPCR activity through a direct Gαi-TRPC interaction.

    Advantages:

• Cell-based assay presents the epitope in its native conformation state

• More physiologically relevant assay conditions

• Highly sensitive, robust signal, and adaptable to various high throughput screen formats

• Well suited not only for screening for agonists/antagonists, but also for screening for allosteric regulators, partial agonists/antagonists



Displaying products 1 - 25 of 71 results
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Amylin 3 Receptor (AMY3) ACTOneTM Stable Cell
CL-01-AMY3
$4,999.00
Calcitonin Receptor (CALCR) ACTOne Stable Cell Line
CL-01-CALCR
$4,999.00
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