ACTOne PDE Assay is a live cell based cAMP biosensor detection system using a constitutively active GPCR(Gs) as a driving force for cAMP production.
• Highly sensitive and big assay windows
• PDE inhibitor assays at near physiological conditions
• Excellent signal-to-noise ratio and reproducibility
• Real time kinetic assay or end point assay
• Work for both endogenous or recombinant PDEs
Click below for an 11-page-ppt overview of the technology: