CL-01-AMY3

Name

Description

This cell line expresses a recombinant human RAMP3. The parental cell line is Calcitonin Receptor (CALCR) ACTOne Stable Cell Line (CL-01-CALCR) that is HEK-293-CNG cell line that expresses a recombinant human CALCR. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.

Application

cAMP assay for Gs-coupled human Amylin 3 receptor 

Size

1x 10⁶ cells (before freezing)

Detection

FlexStation or Microplate reader

For Downloading

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