Selected Citations:
1)  Spillover of ebolaviruses into people in eastern Democratic Republic of Congo prior to the 2018 Ebola virus disease outbreak. One Heal. Outlook 2, 1–10 (2020).
2) Characterization of rVSVΔG-ZEBOV-GP glycoproteins using automated capillary western blotting. Vaccine 38, 7166–7174 (2020). 
3) Discovery of a new ebolavirus (Bombali virus) in molossid bats in Sierra Leone. Nat. Microbiol. 3, 1084 (2018). 

About the Anti-GP (Zaire Ebola Virus 2014) Rabbit Polyclonal Antibody

Zaire ebolavirus glycoprotein (GP) is the only surface protein expressed on the Ebola virion and serves as the primary mediator of host-cell attachment, receptor interaction, membrane fusion, and viral entry. Because GP is exposed on the viral surface and is essential for infection, it represents the major target of protective immune responses, neutralizing antibodies, vaccine development programs, and antiviral therapeutic strategies. Numerous studies have demonstrated that antibodies directed against Ebola virus GP can effectively recognize viral antigens and contribute to the characterization of protective immune responses. Therapeutic antibody cocktails approved for the treatment of Ebola virus disease also target the viral glycoprotein, highlighting its importance in both basic and translational research.

eEnzyme's Anti-GP (Zaire Ebola Virus 2014) Rabbit Polyclonal Antibody is generated against the glycoprotein of the 2014 outbreak strain and provides a valuable research reagent for the detection, characterization, and analysis of Ebola virus GP. This antibody is suitable for Western blotting, ELISA, immunoprecipitation, and other immunological applications. Researchers can utilize this antibody to investigate Ebola virus pathogenesis, evaluate vaccine-induced immune responses, characterize recombinant glycoprotein preparations, and support the development of diagnostic, therapeutic, and vaccine-related technologies.

Applications of the Anti-GP Rabbit Polyclonal Antibody

• Western blot analysis of Ebola virus glycoprotein
• ELISA-based antigen detection and quantification
• Immunoprecipitation and protein characterization
• Vaccine development and evaluation studies
• Filovirus immunology and pathogenesis research
• Antibody validation and assay development

Biological Significance of Ebola Virus Glycoprotein

The Ebola virus glycoprotein is responsible for mediating viral entry into host cells and contains the major antigenic determinants recognized by protective antibodies. During infection, GP facilitates host-cell attachment and membrane fusion, enabling viral replication and spread. Because GP is the principal target of vaccine-induced immunity and antibody-based therapeutics, it remains one of the most extensively studied viral antigens in filovirus research. Antibodies directed against GP are widely used to investigate viral biology, evaluate immune responses, and support the development of vaccines and therapeutic countermeasures against Ebola virus disease.