The A29L protein is a highly conserved membrane protein of Monkeypox virus (MPXV) and other orthopoxviruses. It is the homolog of the vaccinia virus A27L protein and is associated with the intracellular mature virion (IMV) form of the virus. A29L plays an important role in viral attachment to host cells through interactions with cell-surface glycosaminoglycans, facilitating viral entry and infection. Because A29L is highly immunogenic and well conserved among orthopoxviruses, it has become an important target for vaccine development, neutralizing antibody discovery, and diagnostic assay development.

eEnzyme's Anti-Monkeypox Virus A29L Mouse Monoclonal Antibody specifically recognizes the MPXV A29L protein and is suitable for applications including ELISA, virus neutralization assays, antigen detection, vaccine evaluation, and basic orthopoxvirus research. This monoclonal antibody provides a valuable reagent for studies of Monkeypox virus biology, host immune responses, and the development of antiviral therapeutics.