Cannabinoid Receptor 1 (CB1) ACTOne Stable Cell Line

Catalog Number:
CL-11-CB1
Price: Please inquire order@eEnzyme.com
Detailed Description

CL-11-CB1

Name

Cannabinoid Receptor 1 (CB1) ACTOneTM Stable Cell Line

Description

This cell line is a HEK-293-CNG cell line that expresses a recombinant human CB1. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FDSS, FLIPR, or a fluorescence microplate reader.

Application

cAMP dependent human CB1 receptor cell-based assay;

Cell-based high-throughput screening of human CB1 receptor agonists/antagonists.

Size

2x 106 cells

Detection

FlexStation or microplate reader

For Downloading

==>> DATA SHEET       ==>> MSDS


Selected Citation:
Costain, W. J. et al. Pharmacological characterization of emerging synthetic cannabinoids in HEK293T cells and hippocampal neurons. Eur. J. Pharmacol. 786, 234–245 (2016).

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