Cannabinoid Receptor 1 (CB1) ACTOne Stable Cell Line
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Catalog Number:
CL-11-CB1
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Price: Please inquire order@eEnzyme.com
Detailed Description
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CL-11-CB1
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Name
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Cannabinoid Receptor 1 (CB1) ACTOneTM Stable Cell Line |
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Description
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This cell line is a HEK-293-CNG cell line that expresses a recombinant human CB1. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FDSS, FLIPR, or a fluorescence microplate reader.
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Application
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cAMP dependent human CB1 receptor cell-based assay;
Cell-based high-throughput screening of human CB1 receptor agonists/antagonists.
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Size
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2x 106 cells
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Detection
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FlexStation or microplate reader
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For Downloading
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==>> DATA SHEET ==>> MSDS
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Selected Citation:
Costain, W. J. et al. Pharmacological characterization of emerging synthetic cannabinoids in HEK293T cells and hippocampal neurons. Eur. J. Pharmacol. 786, 234–245 (2016).
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