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Corticotropin-Releasing Hormone Receptor 2 (CRHR2) ACTOne Stable Cell Line

Catalog Number:
CL-01-CRHR2
Price is only valid for academic research use; please quote if for industrial use. Restrictions apply. Please inquire.
Price: $4,999.00
Detailed Description

 

CL-01-CRHR2

Name

Corticotropin-Releasing Hormone Receptor 2 (CRHR2) ACTOneTM Stable Cell Line

Description

This cell line is a HEK-293-CNG cell line that expresses a recombinant human CRHR2. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization.  

Application

cAMP dependent human CRHR2 cell-based assay;

cell-based high-throughput screening of human CRHR2 agonists/antagonists.

Size

1x 106 cells

Detection

FlexStation or Microplate reader

 

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