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Calcitonin Receptor-Like Receptor (CRLR) ACTOneTM Stable Cell

Catalog Number:
CL-01-CRLR
This price is valid for academic research use; please quote if for industrial use. Restrictions apply. Please inquire.
Price: $4,999.00
Detailed Description

 

CL-01-CRLR

Name

 Calcitonin Receptor-like Receptor (CRLR) ACTOneTM Stable Cell Line

Description

This cell line is a HEK-293-CNG cell line that expresses a recombinant human CRLR. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.

Application

cAMP dependent human CRLR cell-based assay;

Cell-based high-throughput screening of human CRLR agonists/antagonists.

Size

1x 106 cells

Detection

FlexStation or microplate reader

 

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