G-protein Coupled Bile Acid Receptor 1 (GPBAR1) ACTOne Stable Cell Line

Catalog Number:
CL-01-GPBAR1
Price: Please inquire order@eEnzyme.com
Detailed Description

CL-01-GPBAR1

Name

G-protein coupled bile acid receptor 1 (GPBAR1) ACTOneTM stable cell line

Description

This cell line is a HEK-293 CNG cell line that expresses a recombinant human GPBAR1. HEK-293 CNG-Slcla3 cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.

Application

cAMP dependent human GPBAR1 cell-based assay;

cell-based high-throughput screening of human GPBAR1 agonists/antagonists.

Size

1x 106 cells

Detection

FlexStation or Microplate reader

For Downloading

==>> DATA SHEET      ==>> MSDS



Synonym: G Protein-Coupled Bile Acid Receptor 1, M-BAR, BG37, TGR5, GPCR19, GPR131, G-Protein Coupled Bile Acid Receptor 1



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