Metabotropic Glutamate Receptor 2 (GRM2) ACTOne Stable Cell Line
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Catalog Number:
CL-11-GRM2
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Price: Please inquire order@eEnzyme.com
Detailed Description
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CL-11-GRM2
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Name
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Metabotropic Glutamate Receptor 2 (GRM2) ACTOneTMStable Cell Line
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Description
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This cell line is a HEK-293 CNG-Slcla3 cell line that expresses a recombinant human GRM2. HEK-293 CNG-Slcla3 cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.
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Application
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cAMP dependent human GRM2 cell-based assay;
cell-based high-throughput screening of human GRM2 agonists/antagonists.
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Sizep>
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1x 106 cells
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Detection
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FlexStation or Microplate reader
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For Downloading
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==>> DATA SHEET ==>> MSDS
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Synonym: Glutamate Metabotropic Receptor 2, GPRC1B, MGLUR2, MGlu2, Glutamate Receptor, Metabotropic 2, Metabotropic Glutamate Receptor 2, Glutamate Receptor Homolog, MGluR2, GLUR2
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