Metabotropic Glutamate Receptor 2 (GRM2) ACTOne Stable Cell Line

Catalog Number:
CL-11-GRM2
Price: Please inquire order@eEnzyme.com
Detailed Description

CL-11-GRM2

Name

Metabotropic Glutamate Receptor 2 (GRM2) ACTOneTMStable Cell Line

Description

This cell line is a HEK-293 CNG-Slcla3 cell line that expresses a recombinant human GRM2. HEK-293 CNG-Slcla3 cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.

Application

cAMP dependent human GRM2 cell-based assay;

cell-based high-throughput screening of human GRM2 agonists/antagonists.

Sizep>

1x 106 cells

Detection

FlexStation or Microplate reader

For Downloading

==>> DATA SHEET      ==>> MSDS


Synonym: Glutamate Metabotropic Receptor 2, GPRC1B, MGLUR2, MGlu2, Glutamate Receptor, Metabotropic 2, Metabotropic Glutamate Receptor 2, Glutamate Receptor Homolog, MGluR2, GLUR2



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