Metabotropic Glutamate Receptor 4 (GRM4) ACTOne Stable Cell Line

Catalog Number:
CL-11-GRM4
Price: Please inquire order@eEnzyme.com
Detailed Description

CL-11-GRM4

Name

Metabotropic Glutamate Receptor 4 (GRM4) ACTOne>TM Stable Cell Line

Description

This cell line is a HEK-293 CNG-Slcla3 cell line that expresses a recombinant human GRM4. HEK-293 CNG-Slcla3 cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.

Application

cAMP dependent human GRM4 cell-based assay;

cell-based high-throughput screening of human GRM4 agonists/antagonists.

Size

1x 106 cells

Detection

FlexStation or Microplate reader

For Downloading

==>> DATA SHEET      ==>> MSDS


Synonym: Glutamate Metabotropic Receptor 4,, GPRC1D, MGLUR4, MGlu4, Metabotropic Glutamate Receptor 4, MGluR4




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