Metabotropic Glutamate Receptor 8 (GRM8) ACTOne Stable Cell Line
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Catalog Number:
CL-11-GRM8
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Price: Please inquire order@eEnzyme.com
Detailed Description
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CL-11-GRM8
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Name
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Metabotropic Glutamate Receptor 8 (GRM8) ACTOneTM Stable Cell Line
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Description
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This cell line is a HEK-293 CNG-Slcla3 cell line that expresses a recombinant human GRM8. HEK-293 CNG-Slcla3 cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.
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Application
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cAMP dependent human GRM8 cell-based assay;
Cell-based high-throughput screening of human GRM8 agonists/antagonists.
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Size
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1x 106 cells
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Detection
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FlexStation or Microplate reader
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For Downloading
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==>> DATA SHEET ==>> MSDS
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Synonym: Glutamate Metabotropic Receptor 8, GPRC1H, MGLUR8, GLUR8, MGlu8, Glutamate Receptor Metabotropic 8, Metabotropic Glutamate Receptor 8, MGluR8
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