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5-Hydroxytryptamine (Serotonin) Receptor 1A (HTR1A) ACTOne Stable Cell Line

Catalog Number:
CL-11-HTR1A
This price is only valid for academic research use; please quote if for industrial use. Restrictions apply. Please inquire.
Price: $4,999.00
Detailed Description

 

CL-11-HTR1A

Name

5-Hydroxytryptamine (Serotonin) Receptor 1A (HTR1A) ACTOneTM Stable Cell Line

Description

This cell line is a HEK-293-CNG cell line that expresses a recombinant human HTR1A. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization.  

Application

cAMP dependent human HTR1A cell-based assay;

cell-based high-throughput screening of human HTR1A agonists/antagonists.

Size

1x 106 cells

Detection

FlexStation or Microplate  reader

 

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