5-Hydroxytryptamine (Serotonin) Receptor 4 (HTR4) ACTOne Stable Cell Line

Catalog Number:
CL-01-HTR4
Price: Please inquire order@eEnzyme.com
Detailed Description

CL-01-HTR4

Name

5-Hydroxytryptamine (Serotonin) Receptor 4 (HTR4)  ACTOneTM Stable Cell Line

Description

This cell line is a HEK-293-CNG cell line that expresses a recombinant human HTR4. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.

Application

cAMP dependent human HTR4 cell-based assay;

Cell-based high-throughput screening (HTS) of human HTR4 agonists/antagonists

Size

1 mL (frozen cells; 1x 106 cells before freezing)

Detection

FlexStation or Microplate reader

Detection

==>> DATA SHEET      ==>> MSDS



Synonym: 5-Hydroxytryptamine Receptor 4, 5-HT4, 5-Hydroxytryptamine (Serotonin) Receptor 4 G Protein-Coupled, 5-Hydroxytryptamine (Serotonin) Receptor 4, Cardiac 5-HT4 Receptor, Serotonin Receptor 4, 5-HT4R, 5-HT-4


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