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5-Hydroxytryptamine (Serotonin) Receptor 4 (HTR4) ACTOne Stable Cell Line
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Catalog Number:
CL-01-HTR4
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Price: Please inquire order@eEnzyme.com
Detailed Description
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CL-01-HTR4
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Name
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5-Hydroxytryptamine (Serotonin) Receptor 4 (HTR4) ACTOneTM Stable Cell Line
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Description
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This cell line is a HEK-293-CNG cell line that expresses a recombinant human HTR4. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.
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Application
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cAMP dependent human HTR4 cell-based assay;
cell-based high-throughput screening (HTS) of human HTR4 agonists/antagonists
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Size
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1 mL (frozen cells; 1x 106 cells before freezing)
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Detection
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FlexStation or Microplate reader
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Detection
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==>> DATA SHEET ==>> MSDS
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