About Measles Virus Hemagglutinin (H) Recombinant Protein

Measles virus (MeV) is an enveloped, negative-sense single-stranded RNA virus belonging to the genus Morbillivirus in the family Paramyxoviridae. The Hemagglutinin (H) glycoprotein is one of the two major viral surface glycoproteins and is responsible for attachment to host cell receptors, including SLAMF1 (CD150), nectin-4 (PVRL4), and CD46 (vaccine strains). Binding of the H protein triggers activation of the viral Fusion (F) protein, initiating membrane fusion and viral entry. Because of its essential role in infection and its strong immunogenicity, the H protein is the primary target of neutralizing antibodies and an important antigen for vaccine and diagnostic research.

eEnzyme's Measles Virus Hemagglutinin (H) Recombinant Protein is produced for research use and is suitable for antibody screening, receptor-binding studies, ELISA development, Western blotting, epitope mapping, structural characterization, and measles vaccine research. This recombinant protein provides a valuable reagent for investigating measles virus entry, host immune responses, and the development of vaccines, diagnostics, and antiviral therapeutics.

Applications

Biological Significance of Measles Virus Hemagglutinin

The measles virus H glycoprotein is the viral attachment protein that initiates infection by binding specific host cell receptors and activating the F protein to mediate membrane fusion. As the major surface antigen of measles virus, H contains the principal neutralizing epitopes recognized by protective antibodies and has become a key target for vaccine development, serological diagnostics, and therapeutic antibody research. The Measles Virus Hemagglutinin Recombinant Protein provides a valuable research tool for studies of measles virus biology, immune responses, and the development of next-generation vaccines and antiviral strategies.