Melanocortin Receptor 1 (MC1R) ACTOne Stable Cell Line

Catalog Number:
CL-01-MC1R
Price: Please inquire order@eEnzyme.com
Detailed Description

CL-01-MC1R

Name

Melanocortin Receptor 1 (MC1R)  ACTOneTM Stable Cell Line

Description

This cell line is a HEK-293-CNG cell line that expresses a recombinant human MC1R. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.

Application

cAMP dependent human MC1R cell-based assay;
Cell-based high-throughput screening of human MC1R agonists/antagonists.

Size

1x 106 cells

Detection

FlexStation or Microplate reader

For Downloading

==>> DATA SHEET      ==>> MSDS



Synonym: Melanocortin 1 Receptor, MSH-R, Alpha Melanocyte Stimulating Hormone Receptor, Melanocyte-Stimulating Hormone Receptor, MC1-R, Melanocortin 1 Receptor (Alpha Melanocyte Stimulating Hormone Receptor), Melanocortin Receptor 1, Melanotropin Receptor, SHEP2, CMM5, MSHR



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