Membrane Receptor Stable Cell Lines
Membrane receptors are integral to numerous cellular functions, including molecular transport, signal transduction, energy utilization, and the structural integrity of cells and tissues. Genome sequencing has revealed that approximately 30% of human genes encode membrane receptors. These proteins are also of high pharmacological relevance—nearly half of all approved drugs exert their effects by targeting membrane receptors.
We offer stable HEK293 and CHO-K1 cell lines expressing a wide range of human membrane receptors, providing robust platforms for functional studies, drug screening, and receptor characterization.
All GPCR-stable cell lines are engineered to co-express a modified CNG channel
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PDE stable cell lines engineered to co-express a modified CNG (Cyclic Nucleotide Gated) channel
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Click for the white paper, "Membrane Proteins: Critical Issues in Therapeutic Development"
Selected Citation:
Hammad,et al. MC4R Variant rs17782313 Associates With Increased Levels of DNAJC27, Ghrelin, and Visfatin and Correlates With Obesity and Hypertension in a Kuwaiti Cohort. Front. Endocrinol., 07 July 2020
Please contact us (order@eEnzyme.com) for a quote for constructing custom mambrane receptor stable cell lines.
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