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Adenylate Cyclase Activating Polypeptide 1 Receptor (PAC1R) ACTOne Stable Cell Line

Catalog Number:
CL-01-PAC1R
Price is only valid for academic research use; please quote if for industrial use. Restrictions apply. Please inquire.
Price: $4,999.00
Detailed Description

 

CL-01-PAC1R

Name

Adenylate Cyclase Activating Polypeptide 1 Receptor (PAC1R)  ACTOneTM Stable Cell Line

Description

This cell line is a HEK-293-CNG cell line that expresses a recombinant human PAC1R. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization.  

Application

cAMP dependent human PAC1R cell-based assay;

cell-based high-throughput screening of human PAC1R agonists/antagonists.

Size

1x 106 cells

Detection

FlexStation or Microplate reader

 

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