Prostaglandin i2 Receptor (PTGIR) ACTOne Stable Cell Line
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Catalog Number:
CL-01-PTGIR
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Price: Please inquire order@eEnzyme.com
Detailed Description
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CL-01-PTGIR
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Name
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Prostaglandin I2 Receptor ACTOneTM Stable Cell Line
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Description
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This cell line is a HEK-293-CNG cell line that expresses a recombinant human PTGIR. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.
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Application
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cAMP dependent human PTGIR cell-based assay;
cell-based high-throughput screening of human PTGIR agonists/antagonists.
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Size
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1x 106 cells
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Detection
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FlexStation or Microplate reader
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For Downloading
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==>> DATA SHEET ==>> MSDS
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Synonym: Prostacyclin Receptor, Prostaglandin I2 (Prostacyclin) Receptor (IP). Prostanoid IP Receptor, PGI2 Receptor, PGI Receptor, PRIPR
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