Parathyroid Hormone 1 Receptor (PTH1R) ACTOne Stable Cell Line

Catalog Number:
CL-01-PTH1R
Price: Please inquire order@eEnzyme.com
Detailed Description

CL-01-PTH1R

Name

Parathyroid Hormone 1 Receptor (PTH1R) ACTOneTM Stable Cell Line

Description

This cell line is a HEK-293-CNG cell line that expresses a recombinant human PTH1R. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.

Application

cAMP dependent human PTH1R cell-based assay;

Cell-based high-throughput screening of human PTH1R agonists/antagonists.

Size

1x 106 cells

Detection

FlexStation or Microplate reader

For Downloading

==>> DATA SHEET      ==>> MSDS



Synonym: Parathyroid Hormone 1 Receptor, PTHR1, PTHR, Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor, Parathyroid Hormone Receptor 1, PTH/PTHrP Type I Receptor, PTH/PTHr Receptor, PTH1 Receptor, Parathyroid Hormone/Parathyroid Hormone-Related Protein Receptor, Seven Transmembrane Helix Receptor, EKNS, PFE



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