Sphingosine-1-phosphate Receptor 1 (S1PR1) ACTOne Stable Cell Line
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Catalog Number:
CL-11-S1PR1
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Price: Please inquire order@eEnzyme.com
Detailed Description
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CL-11-S1PR1
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Name
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Sphingosine-1-phosphate Receptor 1 (S1PR1) ACTOneTM Stable Cell Line |
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Description
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This cell line is a HEK-293-CNG cell line that expresses a recombinant human S1PR1. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.
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Application
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cAMP dependent assay for Gi-coupled human S1PR1;
cell-based high-throughput screening of human S1PR1 inhibitors.
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Size
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1x 106 cells
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Detection
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FlexStation or Microplate reader
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For Downloading
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==>> DATA SHEET ==>> MSDS
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Synonym: Sphingosine-1-Phosphate Receptor 1, D1S3362, Edg-1, CD363, EDG1, Endothelial Differentiation Sphingolipid G-Protein-Coupled Receptor 1, Endothelial Differentiation G-Protein Coupled Receptor 1, Sphingosine 1-Phosphate Receptor Edg-1, Sphingosine 1-Phosphate Receptor 1, S1P Receptor Edg-1, S1P Receptor 1, CHEDG1, S1P1, Sphingosine 1-Phosphate Receptor EDG1, CD363 Antigen, ECGF1
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