SARS-CoV-2 Pseudoviral Particles, Omicron Variant
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Catalog Number:
SCV2-PsV-Omicron
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SARS-CoV-2 Pseudoviral Particles, replication-deficient MLV pseudotyped with the SARS-CoV-2 spike protein (the Omicron variant). (Mobile users please click "View Full Site" for details)
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Detailed Description
Keyword: coronavirus, SARS, SARS-Cov, SARS-COV-2, covid19, covid-19, SARS pseudovirus, sars-cov-2 pseudovirus, sars-cov-2 spike, MLV, ace2, Omicron, Omicron variant
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SCV2-PsV-Omicron
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Name
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SARS-CoV-2 Pseudoviral Particles, Omicron Variant (B.1.1.529)
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Description
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The SARS-CoV-2 Pseudoviral Particles we produce are replication-deficient Maloneymurine leukemia virus (MLV or MuLV) pseudotyped with the SARS-CoV-2 spike protein carrying the Omircon variant genotype.
MLV-based virus system is a good for making pseudoviral particles in regards of lab safety and product quality.
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Applications
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Our Pseudovirus Particles generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog # CA-L165), useful for 1) screening potential inhibitors to block SARS-CoV-2 entry and viral protein; 2) measuring the activity of and screening for neutralizing antibody against SARS-CoV-2.
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Size
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5 ml, for one multi-well plate; Pseudoviral particles per mL ~ 1.0E+07
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Storage
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-70oC. Shipped on dry ice.
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Note
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1. Amenable to HTS format (96-well, 384-well and 1536-well format).
2. HEK293-hACE2 stable cells are available seperately (Cat..# CL-hACE2-001, CL-hACE2-002)
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For Downloading
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==>> DATA SHEET ==>> SAFETY DATA SHEET
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Background Knowledge
WHO Statement
Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
26 Nov. 2021
1. "The B.1.1.529 variant was first reported to WHO from South Africa on 24 November 2021. "
2. "The first known confirmed B.1.1.529 infection was from a specimen collected on 9 November 2021."
3. "Current SARS-CoV-2 PCR diagnostics continue to detect this variant."
The "S gene dropout" or "S gene target failure" marker makes it easy to detect the Omicron variant among the positive cases.
 
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