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SARS-CoV-2 Pseudoviral Particles, Omicron Variant

Catalog Number:
SCV2-PsV-Omicron
SARS-CoV-2 Pseudoviral Particles, replication-deficient MLV pseudotyped with the SARS-CoV-2 spike protein (the Omicron variant). (Mobile users please click "View Full Site" for details)
Price: $950.00
Detailed Description
Keyword: coronavirus, SARS, SARS-Cov, SARS-COV-2, covid19, covid-19, SARS pseudovirus, sars-cov-2 pseudovirus, sars-cov-2 spike, MLV, ace2, Omicron, Omicron variant

SCV2-PsV-Omicron

Name

SARS-CoV-2 Pseudoviral Particles, Omicron Variant (B.1.1.529)

Description

The SARS-CoV-2 Pseudoviral Particles are replication-deficient Maloneymurine leukemia virus (MLV or MuLV) pseudotyped with the SARS-CoV-2 spike protein carrying the Omircon variant genotype.
MLV-based virus system is a better choice than HIV-based lentivirus system for making pseudoviral particles in regards of lab safety and product quality. Gag-Pol is the only component from MLV.

Applications

Our Pseudovirus Particles generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog # CA-L165), useful for 1) screening potential inhibitors to block SARS-CoV-2 entry and viral protein; 2) measuring the activity of and screening for neutralizing antibody against SARS-CoV-2. 

Size

10 ml (2 tubes, 5 mL/tube), for 2 multi-well plates. 

Storage

 -70oC. Shipped on dry ice.

Note

1. Amenable to HTS format (96-well, 384-well and 1536-well format). 
2. HEK293-hACE2 stable cells are available seperately (Cat..#  CL-hACE2-001CL-hACE2-002)

For Downloading

==>> DATA SHEET       ==>> SAFETY DATA SHEET



Background Knowledge

WHO Statement
Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
26 Nov. 2021

    1. "The B.1.1.529 variant was first reported to WHO from South Africa on 24 November 2021. "
    2. "The first known confirmed B.1.1.529 infection was from a specimen collected on 9 November 2021."
    3. "Current SARS-CoV-2 PCR diagnostics continue to detect this variant." 
        The "S gene dropout" or "S gene target failure" marker makes it easy to detect the Omicron variant among the positive cases.










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