SARS-CoV-2 Pseudoviral Particles, D614G-A222V

Catalog Number:
SCV2-PsV-222V
SARS-CoV-2 Pseudoviral Particles, replication-deficient MLV pseudotyped with the SARS-CoV-2 spike protein (the 614G-222V variant). (Mobile users please click "View Full Site" for details)
Price: $500.00
Detailed Description
Keyword: coronavirus, SARS, SARS-Cov, SARS-COV-2, covid19, covid-19, SARS pseudovirus, sars-cov-2 pseudovirus, sars-cov-2 spike, MLV, ace2, D614G, 614G, A222V, 222V

SCV2-PsV-222V

Name

SARS-CoV-2 Pseudoviral Particles, D614G-A222V

Description

The SARS-CoV-2 Pseudoviral Particles are replication-deficient Maloneymurine Leukemia Virus (MLV or MuLV) pseudotyped with the SARS-CoV-2 spike protein of the 20E (EU1) variant carrying (Genbank Accession # QHD43416.1, p.222A-->V, p.614D-->G).
MLV-based virus system is a better choice than HIV-based lentivirus system for making pseudoviral particles in regards of lab safety and product quality. Gag-Pol is the only component from MLV.

Applications

Our Pseudovirus Particles generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog # CA-L165), useful for 1) screening potential inhibitors to block SARS-CoV-2 entry and viral protein; 2) measuring the activity of and screening for neutralizing antibody against SARS-CoV-2.

Size

5 ml, for one multi-well plate. Pseudoviral particles per mL ~ 1.0E+07

Storage

 -70oC. Shipped on dry ice.

Note

1. Amenable to HTS format (96-well, 384-well and 1536-well format). 
2. HEK293-hACE2 stable cells are available seperately (Cat.# CL-hACE2-001, CL-hACE2-002)

For downloading

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Reference
:
Spanish-originated SARS-CoV-2 variant A222V shows rapid spread in Lazio, Italy 


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