SCV2-PsV-BR

Name

SARS-CoV-2 Pseudoviral Particles, Gamma Variant (Brazil P.1)  

Description

The SARS-CoV-2 Pseudoviral Particles are replication-deficient Maloneymurine leukemia virus (MLV or MuLV) pseudotyped with the SARS-CoV-2 spike protein of the Gamma variant (Brazil P.1, a.k.a. Gamma, 20J/501Y.V3, VOC-202101/02) (GISAID sequence accession number EPI_ISL_833172). 
MLV-based virus system is a better choice than HIV-based lentivirus system for making pseudoviral particles in regards of lab safety and product quality. Gag-Pol is the only component from MLV.

Applications

Our Pseudovirus Particles generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog # CA-L165), useful for 1) screening potential inhibitors to block SARS-CoV-2 entry and viral protein; 2) measuring the activity of and screening for neutralizing antibody against SARS-CoV-2. 

Size

5 ml, for one multi-well plate. Pseudoviral particles per mL ~ 1.0E+08

Storage

 -70^oC. Shipped on dry ice.

Note

1. Amenable to HTS format (96-well, 384-well and 1536-well format). 
2. HEK293-hACE2 stable cells are available seperately (Cat..#  CL-hACE2-001, CL-hACE2-002)

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