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SARS-CoV-2 Pseudoviral Particles

Catalog Number:
SCV2-PsV-001
SARS-CoV-2 Pseudoviral Particles, replication-deficient MLV pseudotyped with the SARS-CoV-2 spike protein. (Mobile users please click "View Full Site" for details)
Price: $800.00
Detailed Description
Keywords: coronavirus, SARS, SARS-Cov, SARS-COV-2, covid19, covid-19, SARS pseudovirus, sars-cov-2 pseudovirus, sars-cov-2 spike, ace2, SARS-2, new SARS, SARS-Cov-2, nCOV2019, pseudovirus, pseudoviral particle, spike, MLV, LUC

SCV2-PsV-001

Name

SARS-CoV-2 Pseudoviral Particles 

Description

Our SARS-CoV-2 Pseudoviral Particles are replication-deficient Maloneymurine Leukemia Virus (MLV or MuLV) pseudotyped with the SARS-CoV-2 spike protein carrying the original D614 genotype (Genbank Accession # YP_009724390.1). 
MLV-based virus system is a better choice than HIV-based lentivirus system for making pseudoviral particles in regards of lab safety and product quality. Gag-Pol is the only component from MLV.

Applications

Our Pseudovirus Particles generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog # CA-L165), useful for 1) screening potential inhibitors to block SARS-CoV-2 entry and viral protein; 2) measuring the activity of and screening for neutralizing antibody against SARS-CoV-2. 

Size

10 ml (2 tubes, 5 mL/tube), for 2 multi-well plates. Pseudoviral particles per mL ~ 1.0E+08

Storage

 -70 C. Shipped on dry ice.

Note

1. Amenable to HTS format (96-well, 384-well and 1536-well format). Biosafety Level 2.
2. HEK293-hACE2 stable cell lines are available seperately (Cat..#  CL-hACE2-001, CL-hACE2-002)


==>> DATA SHEET

==>> SAFETY DATA SHEET

Reference: Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein, Walls, et al, 2020, Cell 181, 281–292

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