Unlock seamless access to reliable, ready-to-use stable cell lines tailored to your research needs. eEnzyme offers a diverse portfolio of ACTOne™ HEK-293-CNG-based stable cell lines, engineered for robust and consistent signal detection.

Why Choose Our ACTOne™ Stable Cell Lines?

• Broad Receptor Availability — Explore a wide array of human receptors with ready-made cell lines such as:

• GPCRs (e.g., S1PR2, OPRK1, HTR1A, DRD2, ADORA2A, CB1, CXCR4)

• Additional targets, including hACE2 for viral entry studies

• Sensitive, cAMP-Responsive Detection

  Leveraging a modified cyclic nucleotide-gated (CNG) channel, these HEK-293-CNG cells respond to intracellular cAMP fluctuations through ion flux and membrane depolarization for precise, real-time signal capture

• Versatile Screening Applications

  Ideal for cAMP-dependent assays and high-throughput screening of agonists and antagonists — supporting both end-point and kinetic readouts with FLIPR, FDSS, FlexStation, or standard microplate readers

• Technical Convenience

  Each line is readily supplied in frozen aliquots (~1 × 10^6 cells), with certain receptor lines available in larger quantities (e.g., CB1 at 2 × 10^6 cells)

• Transparent and Accessible

  Detailed product sheets and MSDS documents are available for download to support your planning and compliance needs