Stable Cell Line Service
Stable Cell Line Service | eEnzyme
|
eEnzyme offers ready-to-use ACTOne™ HEK-293-CNG-based stable cell lines engineered for reliable receptor expression and sensitive signal detection. The portfolio includes human GPCR targets and additional receptor-expressing cell models for pharmacology, cAMP-responsive assays, viral-entry studies, and high-throughput compound screening.
Available formats support endpoint or kinetic measurements using common fluorescence plate-reading platforms and can be integrated into screening, profiling, and assay-development workflows.
|
Stable Cell Line Workflow
Target Gene
↓
HEK293-Based Host Cells
↓
Stable Selection
↓
Clone / Pool Validation
↓
Assay-Ready Cell Line
|
Cell Line Applications
| GPCR Pharmacology
Agonist and antagonist testing, concentration-response studies, receptor profiling, and compound screening.
|
High-Throughput Screening
Stable and reproducible receptor expression for screening programs using compatible fluorescence platforms.
|
| Viral Entry Studies
Receptor-expressing models for pseudovirus entry, receptor interaction, and related virology applications.
|
Assay Development
Development or transfer of endpoint and kinetic assays for compounds, antibodies, or receptor-response studies.
|
ACTOne™ Platform Principle
ACTOne™ HEK-293-CNG cells use a modified cyclic nucleotide-gated channel to translate intracellular cAMP changes into ion flux and membrane depolarization, enabling sensitive functional detection in endpoint or real-time assay formats.
Find the Right Stable Cell Line
Contact eEnzyme with your receptor target, assay mode, detection platform, and intended application.
Email info@eEnzyme.com
|
|
|