Thyroid Stimulating Hormone Receptor (TSHR) ACTOne Stable Cell Line

Catalog Number:
CL-01-TSHR
Price: Please inquire order@eEnzyme.com
Detailed Description

CL-01-TSHR

Name

Thyroid Stimulating Hormone Receptor (TSHR) ACTOneTM Stable Cell Line

Description

This cell line is a HEK-293-CNG cell line that expresses a recombinant human TSHR. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.

Application

cAMP dependent human TSHR cell-based assay;

cell-based high-throughput screening of human TSHR agonists/antagonists

Size

1x 106 cells

Detection

FlexStation or Microplate reader

For Downloading

==>> DATA SHEET      ==>> MSDS



Synonym: Thyroid Stimulating Hormone Receptor, LGR3, Thyrotropin Receptor, Thyroid-Stimulating Hormone Receptor, Seven Transmembrane Helix Receptor, Thyrotropin Receptor-I HTSHR-I, TSH Receptor, HTSHR-I, CHNG1, TSH-R



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