Thyroid Stimulating Hormone Receptor (TSHR) ACTOne Stable Cell Line
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Catalog Number:
CL-01-TSHR
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Price: Please inquire order@eEnzyme.com
Detailed Description
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CL-01-TSHR
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Name
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Thyroid Stimulating Hormone Receptor (TSHR) ACTOneTM Stable Cell Line
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Description
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This cell line is a HEK-293-CNG cell line that expresses a recombinant human TSHR. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.
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Application
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cAMP dependent human TSHR cell-based assay;
cell-based high-throughput screening of human TSHR agonists/antagonists
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Size
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1x 106 cells
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Detection
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FlexStation or Microplate reader
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For Downloading
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==>> DATA SHEET ==>> MSDS
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Synonym: Thyroid Stimulating Hormone Receptor, LGR3, Thyrotropin Receptor, Thyroid-Stimulating Hormone Receptor, Seven Transmembrane Helix Receptor, Thyrotropin Receptor-I HTSHR-I, TSH Receptor, HTSHR-I, CHNG1, TSH-R
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