Vasoactive Intestinal Peptide Receptor 1 (VIPR1) ACTOne Stable Cell Line

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Vasoactive Intestinal Peptide Receptor 1 (VIPR1) ACTOnTM Stable Cell Line


This cell line is a HEK-293-CNG cell line that expresses a recombinant human VIPR1. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader.


cAMP dependent human VIPR1 cell-based assay;

Cell-based high-throughput screening of human VIPR1 agonists/antagonists.


1x 106 cells


FlexStation or Microplate reader

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Synonym: Vasoactive Intestinal Peptide Receptor 1, VPAC1, VPAC1R, RDC1, HVR1, Vasoactive Intestinal Polypeptide Receptor 1, VIP And PACAP Receptor 1, PACAP Type II Receptor, PACAP-R-2, PACAP-R2, VIP-R-1, Pituitary Adenylate Cyclase Activating Polypeptide Receptor Type II, Pituitary Adenylate Cyclase-Activating Polypeptide Type II Receptor, Type 1 Vasoactive Intestinal Peptide Receptor, VIP Receptor Type I, VPAC1 Receptor, VPCAP1R, VAPC1, V1RG, VIPR, VIRG

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