Description

3′-Azido-3′-Deoxythymidine-5′-Triphosphate

AZT is a widely used antiviral agent. AZT penetrates the cell membrane and is converted into AZT triphosphate which inhibits the reaction of reverse transcription. AZT triphosphate can be used for inhibition of reverse transcription in vitro and for the investigation of polymerase-substrate interactions.

Concentration

1 µmol (100 µl of 10 mM solution)

Formula

C₁₀H₁₃N₅P₃O₁₃, MW 504.2

Purity

96-99% (HPLC)

Storage

-20 ^oC

==>> DATA SHEET

Selected Citation:

Goic, B. et al. Virus-derived DNA drives mosquito vector tolerance to arboviral infection. Nat. Commun. 7, 12410 (2016).