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Caspase 8 Assay Kit (Fluorescence)

Catalog Number:
CA-C158
Price: $249.00
Detailed Description

CA-C158

Name

EliteTM Caspase 8 Assay Kit (Fluorescence)

Description

Caspase 8 is proven to have substrate selectivity for the peptide sequence Ile-Glu-Thr-Asp (IETD). This kit uses (Ac-IETD)2-R110 as a fluorogenic indicator for caspase 8 activity. Cleavage of rhodamine 110 (R110) peptides by caspase 8 generates strong fluorescent R110 that is monitored at the emission between 520 nm and 530 nm with the excitation between 480 nm and 500 nm. This spectral feature makes the kit compatible with the FITC filter set.

Application

The EliteTM Caspase 8 Assay Kit provides all the essential components with an optimized assay protocol. The assay can be readily adapted for high throughput screenings. It can be used to either quantify the activated caspase 8 activities in apoptotic cells or screen the caspase 8 inhibitors.

Size

2 plates (96-well)

Detection

Fluorescence microplate reader

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Click here for MSDS