Ebola Virus

Zaire ebolavirus, more commonly known as Ebola virus (EBOV), is one of six known species within the genus Ebolavirus. Four of the six known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as Ebola virus disease (EVD). 

Ebola virus was at first suspected to be a new "strain" of the closely related Marburg virus. The virus was renamed "Ebola virus" in 2010 to avoid confusion. Ebola virus is the single member of the species Zaire ebolavirus, which is assigned to the genus Ebolavirus, family Filoviridae, order Mononegavirales. The members of the species are called Zaire ebolaviruses.

The EBOV genome is a negative-sense single-stranded RNA, approximately 19kb. It encodes seven structural proteins: nucleoprotein (NP), polymerase cofactor (VP35), (VP40), GP, transcription activator (VP30), VP24, and RNA-dependent RNA polymerase (L). 

Selected Citations of our products:

1) Spillover of ebolaviruses into people in eastern Democratic Republic of Congo prior to the 2018 Ebola virus disease outbreak. One Heal. Outlook 2, 1–10 (2020).
2) Characterization of rVSVΔG-ZEBOV-GP glycoproteins using automated capillary western blotting. Vaccine 38, 7166–7174 (2020). 
3) Serology and behavioral perspectives on Ebola virus disease among bushmeat vendors in equateur, democratic republic of the Congo, after the 2018 outbreak. in Open forum infectious diseases 7, ofaa295 (Oxford University Press US, 2020).