Phosphodiesterase 4 (PDE4) ACTOne Stable Cell Line
|
Catalog Number:
CL-03-PDE4
|
Price: Please inquire order@eEnzyme.com
Detailed Description
CL-03-PDE4
|
Name
|
Phosphodiesterase 4 (PDE4) ACTOne™ Stable Cell Line
|
Description
|
This cell line is a HEK293-CNG cell line that expresses recombinant human PDE4 (mainly 4B and 4D). HEK293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently results in ion flux and cell membrane depolarization.
|
Application
|
cAMP dependent human PDE4 cell-based assay;
Cell-based high-throughput screening of human PDE4 agonists/antagonists.
|
Size
|
1x 106 cells
|
Detection
|
FlexStation or Microplate reader
|
For Downloading
|
==>> DATA SHEET
|
|
|
|