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Phosphodiesterase 1B (PDE1B) ACTOne Stable Cell Line

Catalog Number:
CL-03-PDE1B
The price is only valid for academic research use; please quote if for industrial use. Restrictions apply. Please inquire.
Price: $6,999.00
Detailed Description

CL-03-PDE1B

Name

Phosphodiesterase 1B (PDE1B) ACTOneTM Stable Cell Line

Description

This cell line is a HEK293-CNG-Gs cell line that expresses a recombinant human PDE1B. HEK293-CNG-Gs cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently results in ion flux and cell membrane depolarization.  

Application

cAMP dependent human PDE1B cell-based assay;

cell-based high-throughput screening of human PDE1B agonists/antagonists

Size

1x 106 cells

Detection

FlexStation or Microplate reader

 

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