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Phosphodiesterase 1C (PDE1C) ACTOne Stable Cell Line

Catalog Number:
CL-03-PDE1C
The price is only valid for academic research use; please quote if for industrial use. Restrictions apply. Please inquire.
Price: $6,999.00
Detailed Description

 

CL-03-PDE1C

Name

Phosphodiesterase 1C (PDE1C) ACTOneTM Stable Cell Line

Description

This cell line is a HEK293-CNG-sGC cell line that expresses a recombinant human PDE1C. HEK293-CNG-Gs cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization.  

Application

cAMP dependent human PDE1C cell-based assay;

cell-based high-throughput screening of human PDE1C agonists/antagonists.

Size

1x 106 cells

Detection

FlexStation or Microplate reader

 

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