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Phosphodiesterase 4 (PDE4) ACTOne Stable Cell Line

Catalog Number:
CL-03-PDE4
The price is only valid for academic research use; please quote if for industrial use. Restrictions apply. Please inquire.
Price: $6,999.00
Detailed Description

 

CL-03-PDE4

Name

Phosphodiesterase 4 (PDE4) ACTOneTM Stable Cell Line

Description

This cell line is a HEK293-CNG cell line that expresses a recombinant human PDE4. HEK293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently results in ion flux and cell membrane depolarization.  

Application

cAMP dependent human PDE4 cell-based assay;

cell-based high-throughput screening of human PDE4 agonists/antagonists.

Size

1x 106 cells

Detection

FlexStation or Microplate  reader

 

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