About Influenza A Virus Hemagglutinin 1 (HA1) Recombinant Protein (A/Brisbane/10/2007, H3N2)

Influenza A virus is an enveloped, negative-sense segmented RNA virus belonging to the family Orthomyxoviridae. Hemagglutinin (HA) is the major viral surface glycoprotein responsible for viral attachment to sialic acid-containing receptors on host cells and initiation of membrane fusion during viral entry. The HA1 subunit contains the receptor-binding domain and the major antigenic sites recognized by neutralizing antibodies, making it the principal target of protective immune responses and seasonal influenza vaccines. The A/Brisbane/10/2007 (H3N2) strain has been widely used as a reference strain for influenza surveillance, vaccine development, and antigenic characterization.

eEnzyme's Influenza A/H3N2 HA1 Recombinant Protein (A/Brisbane/10/2007) is produced for research use and is suitable for antibody screening, receptor-binding studies, ELISA development, Western blotting, epitope mapping, structural characterization, and influenza vaccine research. This recombinant protein provides a valuable reagent for investigating influenza virus biology, host immune responses, and antiviral therapeutic development.

Applications

Biological Significance of Influenza HA1

The HA1 subunit mediates recognition of host cell receptors and contains the dominant antigenic epitopes targeted by neutralizing antibodies. Because HA1 undergoes frequent antigenic variation, it plays a central role in influenza virus evolution and the annual updating of seasonal influenza vaccines. The Influenza A/H3N2 HA1 Recombinant Protein (A/Brisbane/10/2007) provides a valuable research tool for studies of influenza pathogenesis, immune responses, vaccine evaluation, and diagnostic assay development.