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Phosphodiesterase 4D (PDE4D) ACTOne Stable Cell Line

Catalog Number:
CL-02-PDE4D
Price: Please inquire order@eEnzyme.com
Detailed Description

CL-02-PDE4D

Name

Phosphodiesterase 4D (PDE4D) ACTOne™ Stable Cell Line

Description

This cell line is a CHO-K1-CNG cell line that expresses a recombinant human PDE4D. CHO-K1-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently results in ion flux and cell membrane depolarization.

Application

cAMP dependent human PDE4D cell-based assay;

cell-based high-throughput screening of human PDE4D agonists/antagonists.

Size

1x 106 cells

Detection

FlexStation or Microplate reader

For Downloading

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