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Phosphodiesterase 1B (PDE1B) ACTOne Stable Cell Line, CHO
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Catalog Number:
CL-02-PDE1B
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Price: Please inquire order@eEnzyme.com
Detailed Description
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CL-02-PDE1B
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Name
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Phosphodiesterase 1B (PDE1B) ACTOne™ Stable Cell Line
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Description
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This cell line is a CHO-CNG-sGC cell line that expresses a recombinant human PDE1B. HEK293-CNG-Gs cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently results in ion flux and cell membrane depolarization.
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Application
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cGMP dependent human PDE1B cell-based assay;
cell-based high-throughput screening of human PDE1B agonists/antagonists.
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Size
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1x 106 cells
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Detection
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FlexStation or Microplate reader
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For Downloading
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==>> DATA SHEET
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